I installed the new beta of virtual box for OS X and installed Vista on it for a test. It is quite stable itself, but OS X gets a little unstable. Its the first time I saw OS X freeze up. This happens when removing an external monitor I had attached to the macbook pro. At first I thought it was freezing up completely. However, when playing a video from a DVD, the audio kept playing and only the display seemed to freeze up. I guess the display driver has problems.
Another weird problem is that firefox fails to exit cleanly after I running virtualbox. I have to "force quit".
Other than that, the virtual machine itself is quite stable. Its still beta and I hope they will have these issues cleared soon.