I read most feeds in Google reader, but their are some feeds that I like reading less often. These are feeds that have less interesting content, or too much content (blogs.msdn.com). For those feeds I use Netnewswire (liferea on Linux, haven't found a good enough free reader on Windows though).
But Google Reader has ingrained in me the j/k keys. Unfortunately on Netnewswire the j key marks all unread articles as read. I often press the 'j' key by mistake, and all the hundreds of unread articles are gone!