I've been using Vista RTM consecutively for a few days, and its been very stable. The font display is amazing.
However, today I experienced my first problem with the system. I've been watching a couple of screencasts in quicktime, and IE7 stoped responding. The only new thing that I've done is install the latest version of JDK from java.sun.com. I don't know if its related, or its something else, such as quicktime, but its happened twice in an hour or so.
I've noticed when you visit different sites using IE7, they sometimes ask for various different versions of msxml. A popup appears on the top of the window. Similar to the popup when you try to download a file. The web page itself seems to display properly.